Our Approach: Integrating Engineering into Cancer Research

We’re infusing engineering into cancer clinical trials, so more trials lead to cancer treatments.

Finding a better way

A recent analysis revealed that only five percent of new therapies entering Phase I clinical trials for solid tumor oncology go on to receive FDA approval.

Meanwhile, other high-tech industries are driving rapid technological innovation with far higher success rates.

While engineers are driving product development in high-tech industries, they’re largely absent from clinical science.

We’re on a mission to change that.

How we're reimagining the way cancer treatments are developed

Integrating physics

We use integrated, advanced experimental systems and computational simulation to help identify therapeutic design flaws early in the therapy development process, when they can still be corrected.

An iterative development process is critical. The Wright Brothers weren’t successful until their sixth prototype, while SpaceX quickly cycled through 15 prototypes before successfully taking off and landing their Mars-capable rocket.

Iterating along the way

Innovations in other high-tech industries—from aerospace to computer chips to medical devices—take an interactive approach to product development.

From linear to iterative

Yet clinical science typically takes a linear approach. Typically, the concept is developed and then works to reach as many milestones as it can, from multiple trials to FDA approval. If the therapy fails at any point, it’s abandoned.

Iterative prototyping increases a therapy’s success rate as it advances through each phase of the therapeutic development process.

Two models comparing a traditional linear approach, with efficacy and safety steps happening sequentially, with an iterative approach showing these steps happening in a circular/iterative process

Our Approach: Integrating Engineering into Cancer Research

How we're reimagining the way cancer treatments are developed

Integrating physics

Constraints we work within